Idiom: Lose One's WitsCheck definitions of...loseoneswitsMeaningsTo become irrational; lose one's mind or sense of reason.A-Z Proximitieslose one's headlose one's mindlose one's shirtlose one's temperlose one's touch lose one's wits lose the belllose the number of one's messlose touchloss of facelost causeSimilar Idiomslose one's witshave one's wits about onelose one's coollose one's headlose one's mindlose one's shirtlose one's temperlose one's touchlose the number of one's messbe someone's to loselose facelose groundlose itlose the belllose touchwin the battle, but lose the warSimilar Phrasesbattle of witslose itlose sight oflose track