Anagrams of: UNORIGINATED

• come into existence; take on form or shape

• bring into being

• begin a trip at a certain point, as of a plane, train, bus, etc.

• add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb

• modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished

• make (alcohol) unfit for drinking without impairing usefulness for other purposes

• emotionally hardened

• become fixed or established

• make hard or harder

• become hard or harder

• cause to accept or become hardened to; habituate

• leave a train

• a crafty and involved plot to achieve your (usually sinister) ends

• a clandestine love affair

• cause to be interested or curious

• form intrigues (for) in an underhand manner

• projecting inward