Anagrams of: SIGNORES

• an Italian title of respect for a man; equivalent to the English `sir'; used separately (not prefixed to his name)

• (astronomy) the disappearance of a celestial body prior to an eclipse

• the act of entering

• devote (oneself) fully to

• consume all of one's attention or time

• the extended spatial location of something

• a part of an animal that has a special function or is supplied by a given artery or nerve

• a large indefinite location on the surface of the Earth

• the approximate amount of something (usually used prepositionally as in `in the region of')

• a knowledge domain that you are interested in or are communicating about

• a person who sings

• United States inventor of an improved chain-stitch sewing machine (1811-1875)

• United States writer (born in Poland) of Yiddish stories and novels (1904-1991)

• carnivore of Central America and South America resembling a weasel with a greyish-white back and dark underparts

• refuse to acknowledge

• bar from attention or consideration

• fail to notice

• give little or no attention to

• be ignorant of or in the dark about

• leave (a job, post, or position) voluntarily

• give up or retire from a position

• part with a possession or right

• accept as inevitable