Anagrams of: HEARTANDSOUL

• the central region of a country or continent; especially a region that is important to a country or to a culture

• any region lying in or toward the south

• having a lower part projecting beyond the upper

• To draw or remove a thread from.

• To loosen the connections of.

• To make one's way through.

• the cardinal number that is the product of 10 and 100

• denoting a quantity consisting of 1,000 items or units

• the part of the body between the neck and the upper arm

• a cut of meat including the upper joint of the foreleg

• a ball-and-socket joint between the head of the humerus and a cavity of the scapula

• the part of a garment that covers or fits over the shoulder

• a narrow edge of land (usually unpaved) along the side of a road

• lift onto one's shoulders

• push with the shoulders

• carry a burden, either real or metaphoric

• an archipelago of about 100 islands in the North Atlantic off the north coast of Scotland

• a small sheepdog resembling a collie that was developed in the Shetland Islands