Anagrams of: DESPERATENESSES

• skillful performance or ability without difficulty

• capable of depressing physiological or psychological activity or response by a chemical agent

• a drug that reduces excitability and calms a person

• capable of depressing physiological or psychological activity or response by a chemical agent

• a drug that reduces excitability and calms a person

• a trait of dignified seriousness

• One who is noted for being very fast.

• A person who speeds (drives fast).

• A vehicle or other device used for racing.

• the intellectual ability to penetrate deeply into ideas

• the quality of being physically deep

• the extent downward or backward or inward

• a low pitch that is loud and voluminous