Anagrams of: BENIGNEST

• (superlative of `good') having the most positive qualities

• the supreme effort one can make

• Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)

• the person who is most outstanding or excellent; someone who tops all others

• in a most excellent way or manner

• it would be sensible

• from a position of superiority or authority

• (comparative and superlative of `well') wiser or more advantageous and hence advisable

• get the better of

• a deep-fried, yeast-raised doughnut dusted with confectioners' sugar

• not dangerous to health; not recurrent or progressive (especially of a tumor)

• pleasant and beneficial in nature or influence

• kindness of disposition or manner

• make (offspring) by reproduction

• Israeli statesman (born in Russia) who (as prime minister of Israel) negotiated a peace treaty with Anwar Sadat (then the president of Egypt) (1913-1992)

• take the first step or steps in carrying out an action

• have a beginning, in a temporal, spatial, or evaluative sense

• set in motion, cause to start

• begin to speak or say

• be the first item or point, constitute the beginning or start, come first in a series

• have a beginning, of a temporal event

• have a beginning characterized in some specified way

• begin an event that is implied and limited by the nature or inherent function of the direct object

• achieve or accomplish in the least degree, usually used in the negative

• begin to speak, understand, read, and write a language

• the state or fact of existing

• a living thing that has (or can develop) the ability to act or function independently

• any act of immoderate indulgence

• an occasion for excessive eating or drinking

• overeat or eat immodestly; make a pig of oneself

• to watch a large amount of media in a single seating