Anagrams of: ADMINICULATING

• chew (food); to bite and grind with the teeth

• end, especially to reach a final or climactic stage

• bring to a head or to the highest point

• reach the highest or most decisive point

• reach the highest altitude or the meridian, of a celestial body

• rise to, or form, a summit

• (of a leaf shape) narrowing to a slender point

• make sharp or acute; taper; make (something) come to a point

• make sour or more sour

• morally blemished; stained or impure

• spotted or blotched

• make dirty or spotty, as by exposure to air; also used metaphorically

• spot, stain, or pollute

• be a signal for or a symptom of

• indicate a place, direction, person, or thing; either spatially or figuratively

• to state or express briefly

• give evidence of

• suggest the necessity of an intervention; in medicine

• shackle that consists of a metal loop that can be locked around the wrist; usually used in pairs

• confine or restrain with or as if with manacles or handcuffs