Sentences with 5-HYDROXY-3-METHYLGLUTARYL-COENZYME-A-REDUCTASE
Check out our example sentences below to help you understand the context.Sentences
1
"5-hydroxy-3-methylglutaryl-coenzyme a reductase plays a crucial role in cholesterol synthesis."
2
"Statins are drugs that target 5-hydroxy-3-methylglutaryl-coenzyme a reductase to lower cholesterol levels."
3
"The inhibition of 5-hydroxy-3-methylglutaryl-coenzyme a reductase can lead to reduced production of mevalonate."
4
"The expression of 5-hydroxy-3-methylglutaryl-coenzyme a reductase is regulated by sterol-responsive element-binding proteins."
5
"Studies have shown that 5-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors can reduce the risk of cardiovascular diseases."
6
"5-hydroxy-3-methylglutaryl-coenzyme a reductase is a key enzyme in the mevalonate pathway."
7
"The activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase can be modulated by phosphorylation."
8
"Researchers are studying the structural characteristics of 5-hydroxy-3-methylglutaryl-coenzyme a reductase."
9
"The gene encoding 5-hydroxy-3-methylglutaryl-coenzyme a reductase is located on chromosome X."
10
"Mutations in the 5-hydroxy-3-methylglutaryl-coenzyme a reductase gene can lead to familial hypercholesterolemia."
11
"5-hydroxy-3-methylglutaryl-coenzyme a reductase catalyzes the conversion of HMG-CoA to mevalonate."
12
"The structure of 5-hydroxy-3-methylglutaryl-coenzyme a reductase has been elucidated using X-ray crystallography."
13
"The activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase is regulated by feedback inhibition."
14
"5-hydroxy-3-methylglutaryl-coenzyme a reductase is a membrane-bound protein found in the endoplasmic reticulum."
15
"The rate of cholesterol synthesis is dependent on the activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase."
16
"5-hydroxy-3-methylglutaryl-coenzyme a reductase is a target for drug development to treat hypercholesterolemia."
17
"The enzyme activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase can be measured using spectrophotometry."
18
"The regulation of 5-hydroxy-3-methylglutaryl-coenzyme a reductase is complex and involves multiple signaling pathways."
19
"The statin class of drugs inhibits 5-hydroxy-3-methylglutaryl-coenzyme a reductase."
20
"5-hydroxy-3-methylglutaryl-coenzyme a reductase is a potential therapeutic target for the treatment of cancer."
1
"5-hydroxy-3-methylglutaryl-coenzyme a reductase is a key enzyme in the biosynthesis of cholesterol."
2
"Statins are drugs that inhibit 5-hydroxy-3-methylglutaryl-coenzyme a reductase."
3
"The activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase can be regulated by phosphorylation."
4
"Mutations in the gene encoding 5-hydroxy-3-methylglutaryl-coenzyme a reductase can lead to familial hypercholesterolemia."
5
"The synthesis of 5-hydroxy-3-methylglutaryl-coenzyme a reductase is regulated by the sterol regulatory element-binding protein."
6
"5-hydroxy-3-methylglutaryl-coenzyme a reductase catalyzes the conversion of HMG-CoA to mevalonate."
7
"Liver cells are rich in 5-hydroxy-3-methylglutaryl-coenzyme a reductase due to their role in cholesterol synthesis."
8
"High levels of 5-hydroxy-3-methylglutaryl-coenzyme a reductase activity can contribute to the development of atherosclerosis."
9
"The activity of 5-hydroxy-3-methylglutaryl-coenzyme a reductase is negatively regulated by cholesterol feedback inhibition."
10
"Pharmaceutical companies have developed inhibitors targeting 5-hydroxy-3-methylglutaryl-coenzyme a reductase as cholesterol-lowering drugs."
